What is antimicrobial resistance?

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Antimicrobial resistance happens when microorganisms (such as bacteria, fungi, viruses, and parasites) change when they are exposed to antimicrobial drugs (such as antibiotics, antifungals, antivirals, antimalarials, and anthelmintics). Microorganisms that develop antimicrobial resistance are sometimes referred to as “superbugs”. 

As a result, the medicines become ineffective and infections persist in the body, increasing the risk of spread to others. 

Why is antimicrobial resistance a global concern? 

New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases, resulting in prolonged illness, disability, and death. 

Without effective antimicrobials for prevention and treatment of infections, medical procedures such as organ transplantation, cancer chemotherapy, diabetes management and major surgery (for example, caesarean sections or hip replacements) become very high risk. 

Antimicrobial resistance increases the cost of health care with lengthier stays in hospitals and more intensive care required. 

Antimicrobial resistance is putting the gains of the Millennium Development Goals at risk and endangers achievement of the Sustainable Development Goals. 

What accelerates the emergence and spread of antimicrobial resistance? 

Antimicrobial resistance occurs naturally over time, usually through genetic changes. However, the misuse and overuse of antimicrobials is accelerating this process. In many places, antibiotics are overused and misused in people and animals, and often given without professional oversight. Examples of misuse include when they are taken by people with viral infections like colds and flu, and when they are given as growth promoters in animals or used to prevent diseases in healthy animals. 

Media Contact:  

Liza Parker 
Journal Manager  
Microbiology: Current Research 
Email: aamcr@microbialjournals.com